Chimeric antigen receptor (Car or truck) therapy focusing on CD19 has yielded remarkable outcomes in individuals with acute lymphoblastic leukemia. To discover potential Car or truck targets in acute myeloid leukemia (AML), we probed the AML surfaceome for overexpressed molecules with tolerable systemic expression. We built-in large transcriptomics

????? ???? ??? ???? ??? ???? ?? ???? ????? ????. ????? ??? ??? ??? ??? ? ????????? ?? ?? ??? ???? ?? ??????. ??? ?? ??? ?????? ?? ???? ???, ? ??? ??? ??? ??? ???? ?? ??? ???? ?? ??? ? ??? ?????.????? ?????? ???? ??? ? ?? ??? ???? ?? ???? ????. ?? ??? ??? ? ?? ???? ????, ???? ??? ??? ???? ???????.????? ?? ??? ??? ??? ??? ??? ‘???’ ?? ‘????’

?? ??? ???? ??? ???? ???? ??? ????? ?????? ?????? ?? ?? ??? ????? ? ?? ??? ??? ???? ?????.????? ??? ?????? ?? ??? ?? ??? ??? ? ? ????. ???? ? ? ???? ?????? ???? ????? ??? ??? ?? ????? ?????.?? ?? ????? ???? ????? ??? ???? ???? ????? ????????? ? ? ?? ????? ?? ??? ????? ????? ?? ? ?? ?????? ???? ????.?? ?????? ?????? ??? ????? ???? ??? ??? ?????????.

????? ? ?? ????? ?????? ?????? ???? ???? ????? ?? ?????? ??? ????? ?? ???? ??? ?? ??? ????? ??????.?????? ?????? ??? ???? ?????? ???? ??? ???? ??? ?? ? ????.????? ?? ?????? ???? ????? ???? ??? ????? ?? ???? ? ??? ??? ??? ????? ????.? ? ????? ??? ?????? ???? ????? ??? ????. ?????.???,??,?? ? ???? ???? ?? ????? ???? ? ?? ???? ????? ?????? ?? ? ?????

??? ??? ???? ??? ??? ???? ? ??? ??? ??? ? ? ?? ?????.???? ?? ??? ????? ????? ????? ?????? ??? ??? ???? ??? ??? ??? ???? ??????.??? ????? ?????? ?? ??? ? ?? ???? ???? ????? ?? ??? ????? ? ??? ?? ??? ??? ??? ?? ? ??? ??? ??? ??? ???? ??? ??????.#???????#???????#??????#??????#?????#?????#????#?????#?????#???????#???????#?????????????? ???? ???? ???? ?